141112-29-0
　

Structure:

Technical Isoxaflutole is a yellow granular powder with a slight acetic acid-like odor. Water Solubility: 6.2 mg/l at 20 C. Solubility in Other Solvents: 293g/l in acetone;31.2g/l in toluene;13.8g/l in methanol. Melting Point: 135-136 C. Vapor Pressure: 1 x 10 to the minus 6 Pa at 25 C.
　

The acute oral LD50 for technical Isoxaflutole was reported to be >5000 mg/kg for rats. The dermal LD50 for rabbits exposed to technical Isoxaflutole was >2000 mg/kg. The acute inhalation LC50 for rats exposed to Isoxaflutole is 5.23 mg/L. It was found to be no irritating to the rabbit eye and be no irritating to the skin of male rabbits. Primary Dermal Sensitization in Guinea-Pigs - Did not exhibit any sensitization potential.
　

Isoxaflutole is specifically a soil herbicide, acting pre-emergence. Isoxaflutole is a broad spectrum herbicide, acting on a wide range of annual grasses and broadleaf weeds. The mode of action of isoxaflutole is the inhibition of the enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD), thereby inhibiting pigment formation, and causing bleaching of the developing tissues of the target plants. Isoxaflutole is systemic in its activity, being absorbed roots and leaves.